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भारतीय कृषि अनुसंधान परिषद

Indian Council of Agricultural Research

भा.कृ.अनु.प. – राष्ट्रीय शूकर अनुसंधान केन्द्र

ICAR - National Research Centre on Pig

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Dr. Pranab Jyoti Das

Principal Scientist

Animal Genetics and Breeding

9402283632 / 9101286692
drpranabjyotidas@gmail.com
Pranab.Das@icar.gov.in

Profile Overview:

  • Qualification:

    B.V.Sc. & A.H, M.V.Sc., PhD, Postdoctoral Fellow (USA)
  • Date of Joining NRCP:

    June, 2017
  • About:

    My research is driven by a fundamental question, how can we leverage the power of genetics to ensure the reproductive health and productivity performance of our livestock? This passion for discovery fuels my work in mammalian cytogenetics and functional genomics, with a particular focus on animal genetics and breeding. In my laboratory, I work independently and in collaboration to achieve research goals on time and constantly achieve new skills to progress translational research. Our laboratory is seeking to understand the comparative organization and functional genetics of the mammalian genome by analyzing the genomes of animals with special reference to Pigs. Of particular interest are those regions of the mammalian genome which contain genes that confer infertility, and disease tolerance in animals. Currently, our laboratory is working on functional genomics with a focus on the genomics of mammalian Y chromosomes, and the genomics of reproduction as well as disease genetics. We use approaches that include sequencing of nuclear and mtDNA, microsatellite genotyping and next-generation sequencing to understand the dynamics of populations in the pig. My recent focus is on next-generation sequencing in pig genomic and conservation genetics to understand the important economic traits of pigs. We are also working on the discovery of fertility-related siRNA and their potential role in male infertility in pigs as well as traceability and use of Artificial intelligence to enhance pig production and profitability. Recently, we have also working on the digitization of piggery using AI technology as well as the thermal imaging profile of pigs. I’m seeking potential opportunities in non-profits, molecular biology and genetics-based organizations to engage and contribute to the biotech space as a scientist or research analyst that leverages my distinct technical background and skills towards potential transformative avenues for dealing with gene discovery and understanding mammalian genome. Our laboratory is very well-equipped for molecular biology work and pig genomics. Beyond the lab, my fascination with the intricate dance of life extends to my hobbies. I enjoy delving into the world of conservation genetics, and studying how animals have adapted to challenging environments. It's a constant reminder of the importance of biodiversity and the delicate balance within ecosystems. If you share my passion for agricultural innovation and the power of genetics, I'd love to connect and discuss potential collaborative opportunities. Let's work together to unlock the full potential of our animal companions for a more sustainable and productive future. Area of specialization: Animal Genetics and Breeding (specialization -Animal Genomics)

Technologies Developed:

  1. Artificial Insemination in Pig (Copyright Registered)
  2. Garmin Sukarpalan Ke Uthan Hetu Flim (Copyright Registered)
  3. Mobile App on Artificial Insemination in Pig (Launch in Play store)
  4. PIGGYPLEX (R) CSF,JE & PRRS ASSAY KIT(Copyright & trademark Registered)
  5. PIGGYPLEX(D) ASFV,PCV &PPV ASSAY KIT (Copyright & Trademark Registered, ICAR-Certification)
  6. Scientific Pig Production Practice (Copyright Registered)
  7. Yak Hair Based Carpet Products (ICAR-Certification)
  8. Yak Hair Based Carpet Products (ICAR-Certification)
  9. Boar semen preservation and transportation box (Design Registered)
  10. Boar semen preservation cabinet (Design Registered)

Technologies Commercialized:

Not Available

Publications:

  • Total no. of Research Paper: 101
  • Total no. of Books/Manual: 10
  • No. of patent /Trademark granted (G) /Design (G): 05
  • Copyright granted: 05
  • Policy Document: 01

Top 10 Research Publications:

  1. 1. Das, P. J., Kumar, S., Choudhury, M., Banik, S., Pegu, S. R., Kumar, S., Deb, R., & Gupta, V. K. (2024). Characterization of the complete mitochondrial genome and identification of signature sequence of Indian wild pig. Gene, 897, 148070. https://doi.org/10.1016/j.gene.2023.148070.
  2. 2. Das, P.J.; Kour, A.; Deori, S.; Begum, S.S.; Pukhrambam, M.; Maiti, S.; Sivalingam, J.; Paul, V.; Sarkar, M.(2022). Characterization of Arunachali Yak: A Roadmap for Pastoral Sustainability of Yaks in India. Sustainability, 14, 12655. https://doi.org/10.3390/su141912655.
  3. 3. Das, P. J., McCarthy, F., Vishnoi, M., Paria, N., Gresham, C., Li, G., Kachroo, P., Sudderth, A. K., Teague, S., Love, C. C., Varner, D. D., Chowdhary, B. P., & Raudsepp, T. (2013). Stallion Sperm Transcriptome Comprises Functionally Coherent Coding and Regulatory RNAs as Revealed by Microarray Analysis and RNA-seq. PLoS One, 8(2), e56535. https://doi.org/10.1371/journal.pone.0056535.
  4. 4. Das P.J., Paria N., Gustafson-Seabury A., Vishnoi M., Chaki S.P., Love C.C., Varner D.D., Chowdhary B.P., Raudsepp T. (2010) Total RNA isolation from stallion sperm and testis biopsies. Theriogenology.74 (6):1099-1106, 1106e1-2.
  5. 5. Das, P. J., Chowdhary, B. P., & Raudsepp, T. (2009). Characterization of the bovine pseudoautosomal region and comparison with sheep, goat, and other mammalian pseudoautosomal regions. Cytogenetic and genome research, 126(1-2), 139–147. https://doi.org/10.1159/000245913.
  6. 6. Jevit, M.J., Castaneda, C., Paria, N., Das, P.J., Miller, D., Antczak, D.F., Kalbfleisch, T.S. Davis, B. W., Raudsepp, T. (2023) Trio-binning of a hinny refines the comparative organization of the horse and donkey X chromosomes and reveals novel species-specific features. Scientific Report 13, 20180 (2023). https://doi.org/10.1038/s41598-023-47583-x.
  7. 7. Pegu, S.R.; Das, P.J.; Sonowal, J.; Sengar, G.S.; Deb, R.; Yadav, A.K.; Rajkhowa, S.; Choudhury, M.; Gulati, B.R.; Gupta, V.K. .(2023). Japanese Encephalitis Virus Genotype III Strains Detection and Genome Sequencing from Indian Pig and Mosquito Vector. Vaccines 2023, 11, 150. https://doi.org/10.3390/vaccines11010150.
  8. 8. Janečka, J. E., Davis, B. W., Ghosh, S., Paria, N., Das, P. J., Orlando, L., Schubert, M., Nielsen, M. K., Stout, T. A. E., Brashear, W., Li, G., Johnson, C. D., Metz, R. P., Zadjali, A. M. A., Love, C. C., Varner, D. D., Bellott, D. W., Murphy, W. J., Chowdhary, B. P., & Raudsepp, T. (2018). Horse Y chromosome assembly displays unique evolutionary features and putative stallion fertility genes. Nature communications, 9(1), 2945. https://doi.org/10.1038/s41467-018-05290-6.
  9. 9. Raudsepp, T., McCue, M. E., Das, P. J., Dobson, L., Vishnoi, M., Fritz, K. L., Schaefer, R., Rendahl, A. K., Derr, J. N., Love, C. C., Varner, D. D., & Chowdhary, B. P. (2012). Genome-wide association study implicates testis-sperm specific FKBP6 as a susceptibility locus for impaired acrosome reaction in stallions. PLoS genetics, 8(12), e1003139. https://doi.org/10.1371/journal.pgen.1003139.
  10. 10. Baily MP., Avila F ., Das PJ., Kutzler M.A., Raudsepp T(2019).An Autosomal Translocation 73,XY,t(12;20)(q11;q11) in an Infertile Male Llama (Lama glama) With Teratozoospermia. Frontiers in Genetics. doi: 10.3389/fgene.2019.00344.

Awards:

  1. First Prize - Best Book in Agricultural Extension
  2. Best Institutional Film Award 2023, conferred by MANAGE, HYDERABAD
  3. Breed conservation Award (Institute Category-2021) for conservation of Ghoongroo Pig conferred by ICAR-NBAGR, Karnal
  4. Best Presentation Award (First Prize). Girish, P. S., P. J. Das., Nagappa Karabasanavar (2018) Recent Advances in Application of IT in Muscle Food Sector International Symposium, Kolkata from 22nd to 24th November 2018
  5. Breed Registration certificate award (Registration of Arunachali Yak - INDIA_YAK_2300_ARUNACHALI_16001) 2019
  6. Letter of Appreciation for contribution in Animal by ADNAT Silver Jubilee Convention, International Symposium on Biodiversity and Bio banking, IIT, Guwahati, 2018
  7. Reorganization Certificate from Indian Association of Hill Farming (SFEIES-2017)

Membership of Societies:

  1. American Association for the Advancement of Science
  2. Laboratory Animal Science Association of India